It is essential to determine if the isolates are etiological for the source of the infection. Sampling and diagnostic procedures as well as characterisation of the bacterial agents are most important for successful vaccination.
Depending on the problem, the application of the vaccine can be parenteral per injectionem (subcutaneously or intramuscular) or local (per os, per aerosol, per immersionem). Time, intervals and dosage of the vaccine can be handled individually.
The use of autogenous vaccines leads to less application of antibiotics or medical treatment. There are no problems with resistant bacteria or residue of medication. Furthermore, there is no withdrawal period.
It is important to combine the application of autogenous vaccines with other measures such as hygiene management, monitoring or animal welfare.
- commercial vaccines unavailable
- different serotypes of isolates – no cross immunity
- genetic instability – bacteria alter antigenic characteristics – protective effect in commercial vaccines decreases
- rare diseases – rare species (MIMS / MUMS – minor indication / minor use, minor species)